Search on: KV11.1 PROTEIN POTASSIUM CHANNEL 
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Descriptor English:   ERG1 Potassium Channel 
Descriptor Spanish:   Canal de Potasio ERG1 
Descriptor Portuguese:   Canal de Potássio ERG1 
Synonyms English:   Channel, ERG1 Potassium
Channel, Kv11.1 Protein-Potassium
Ether A Go Go Related Potassium Channel 1
Ether-A-Go-Go-Related Potassium Channel 1
Kv11.1 Protein Potassium Channel
Kv11.1 Protein-Potassium Channel
Potassium Channel, ERG1
Potassium Voltage-Gated Channel, Subfamily H, Member 2
Protein-Potassium Channel, Kv11.1  
Tree Number:   D12.776.157.530.400.600.900.249.500
D12.776.543.550.450.750.900.249.500
D12.776.543.585.400.750.900.249.500
Definition English:   One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA. 
History Note English:   2017 (2001) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56585 
Unique Identifier:   D000072237 

Occurrence in VHL: 		 

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